2024 Pebp4 and heart

Pebp4 and heart

Author: eibo

August undefined, 2024

WebThe gene view histogram is a graphical view of mutations across PEBP4. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. WebNov 12, 2011 · PEBP4 is expressed in the mammalian testis, heart, skeletal muscle, thyroid, liver, spinal cord, brain, adrenal gland, and bone marrow [ 14 ], and mainly participates in physiopathological processes such as membrane biosynthesis, neurodevelopment, spermatogenesis, and apoptosis [ 4 ].

Subcellular - PEBP4 - The Human Protein Atlas

WebJan 20, 2024 · Interaction between whitefly PEBP4 and TYLCV CP suppresses phosphorylation of MAPK cascade, activating apoptosis. TYLCV CP liberates PEBP4 … WebPharos : Target Details - PEBP4 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data tspoon harpurhey

The Roles And Signaling Pathways Of Phosphatidylethanolamine …

WebMar 28, 2016 · In mammalian cells, four members of PEBP, ranging from 21–25 kids, have been documented; PEBP1 is ubiquitously expressed at high levels in brain, adrenal gland and thyroid (2, 3), PEBP2 is mostly restricted to testis , PEBP3 has not yet been characterized, and PEBP4 is predominantly expressed in skeletal muscle, heart and thyroid . WebAug 8, 2024 · PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2 PEBP4 Directs the Malignant Behavior of … WebJul 8, 2024 · Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein with multiple biological functions. At present, studies on PEBP4 exist mainly in the field of tumors and rarely in inflammation. This study aimed to explore the potential roles and mechanisms of PEBP4 on lipopolysaccharide (LPS)/D-galactosamine (D-GalN) - induced ALI. phirst park homes lipa sample computation

Phosphatidylethanolamine-binding protein 4 promotes …

Phosphatidylethanolamine binding protein-4 (PEBP4) is …

WebMar 22, 2024 · Serum PEBP4 was high in CKD patients compared with healthy individuals. PEBP4 levels were positively correlated with pathological stage in CKD patients. PEBP4 … WebOct 26, 2024 · Phosphatidylethanolamine-binding protein 4 (PEBP4), a member of the PEBP family, has been reported to play a pivotal role in tumor progression. However, its role in epithelial-to-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) cells remains unclear. Here, we investigated the effects and underlying mechanism of PEBP4 in … phirst park homes main officeWebeffects of PEBP4 on LSCC can be neglected in most cases of LSCC, where PEBP4 demonstrated decreased expression levels. However, in the case of PEBP4 overexpression, it may contribute to the progression of LSCC and lead to the develop - ment of drug resistance. Introduction Lung cancer is a leading cause of cancer-associated mortality phirst park homes laguna

"WebZi-Kang Luo, 1, * Qiong-Feng Chen, 2, * Xiaoqin Qu, 2 Xiao-Yan Zhou 2, 3 1 Department of Clinical Medical, The Second Clinical Medical College, Nanchang University, Nanchang 330006, People’s Republic of China; 2 Department of Pathophysiology, Medical College of Nanchang University, Nanchang, Jiangxi 330006, People’s Republic of China; 3 Jiangxi … " - Pebp4 and heart

Pebp4 and heart

Phosphatidylethanolamine binding protein-4 (PEBP4) is

WebFeb 1, 2007 · PEBP4 (phosphatidylethanolamine binding protein 4) 2007-02-01 Identity HGNC PEBP4 LOCATION 8p21.3 LOCUSID 157310 ALIAS CORK-1, CORK1, GWTM1933, … WebSep 2, 2024 · Phosphatidylethanolamine-binding protein 4 (PEBP4) is a secreted protein involved in regulating many molecular pathways, whereas its roles in diseases including hepatic fibrosis remain undefined. The nuclear factor-κappa B (NF-κB) signaling pathway has been found to be involved in the development of liver fibrosis.

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WebJul 1, 2016 · PEBP4 was first identified as a regulator of the MAPK pathway [5], [20]. Wang et al [5] have shown that PEBP4 interacts with Raf-1 and MEK1 and attenuates activation of … WebPEBP4 appears to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. ... Anti-PEBP4 antibody (ab99468) at 1 µg/ml + Human Heart lysates at 35 µg Predicted band size: 26 kDa.

WebDec 1, 2024 · PEBP4 was identified by proteomics in urine and is increased in IgAN urine and serum. A: LC-MS/MS Proteomics analysis of healthy donor and IgAN patient urine identified 19 lysosomal proteins including PEBP4. Lysosomal proteins were isolated from identified urine proteins using gene ontology and are presented as a colour-coded protein-protein ... WebOct 26, 2024 · Furthermore, PEBP4 overexpression significantly promoted the transcriptional activity of sonic hedgehog (Shh) signaling in NSCLC cells. Further analysis showed that using cyclopamine to inhibit Shh signaling significantly ameliorated the effect on cell proliferation, invasion, and migration, as well as EMT triggered by PEBP4 overexpression.

WebOct 17, 2015 · The PI3K/Akt/mTOR signaling axis may be a key molecular pathway via which PEBP4 promotes the proliferation and invasion of non-small cell lung cancer (NSCLC) … WebMar 22, 2024 · Serum PEBP4 was high in CKD patients compared with healthy individuals. PEBP4 levels were positively correlated with pathological stage in CKD patients. PEBP4 had higher sensitivity for diagnosis of CKD than common indexes including blood urea nitrogen, creatinine and C-reactive protein.

WebPEBP4 was first identified as a regulator of the MAPK pathway (5, 20). Wang et al have shown that PEBP4 interacts with Raf-1 and MEK1 and attenuates activation of MEK1. This …

tsporWeb(E): PEBP4 protein expression was tested by western blotting in the heart, liver, lungs, spleen, and kidneys of WT and CKO mice. Data are presented as mean ± SD values (n = 3). … tsp or fidelityWebSep 2, 2024 · Phosphatidylethanolamine-binding protein 4 (PEBP4) is a secreted protein involved in regulating many molecular pathways, whereas its roles in diseases including hepatic fibrosis remain undefined.... tsp or annuityWebThe phosphatidylethanolamine (PE)-b inding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and … phirst park homes officeWebJul 1, 2016 · In mammalian cells, four members of PEBP, ranging from 21–25 kids, have been documented; PEBP1 is ubiquitously expressed at high levels in the brain, adrenal gland and thyroid [2], [3], PEBP2 is mostly restricted to the testis [4], PEBP3 has not yet been characterized, and PEBP4 is predominantly expressed in the skeletal muscle, heart and ... phirst park homes official facebook pageWebHeart musclei. On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and … phirst park homes pandi logoWebSummary of RNA expression and protein localization based on data generated within the Human Protein Atlas project. Main locationi. Main subcellular location (s) and reliability score (s) for the encoded protein (s) in human cells. The main location (s) may be characterized by presence in all tested cell lines and/or ihigher staining intensity ... phirst park homes reviews